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Copaxone INDICATIONS

Indications and Usage for Copaxone Copaxone is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults. Copaxone Dosage and Administratio COPAXONE is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults

COPAXONE is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive.. Use. COPAXONE ® is a prescription medicine that is used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.. Important Safety Information. Do not use COPAXONE ® if you are allergic to glatiramer acetate or mannitol.. Serious side effects may happen right after or within. COPAXONE is a prescription medicine that is used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults

Copaxone - FDA prescribing information, side effects and use

COPAXONE (glatiramer acetate) solution for subcutaneous injection Initial U.S. Approval: 1996 -----RECENT MAJOR CHANGES----- Indications and Usage (1) 2/2009 -----INDICATIONS AND USAGE----- COPAXONE is indicated for reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis, including patients who have. Indications for COPAXONE: Relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease The standard dosing option continues to be available. Click here to read the FDA Prescribing Information for healthcare professionals. To read the Patient Information, go to the FDA Prescribing Information and scroll down to p. 5. Support. COPAXONE SUPPORT PROGRAM Shared Solutions® 1-800-887-8100 www.copaxone.com www.sharedsolutions.co For all indications: Authorization of 12 months may be granted for members who are experiencing disease stability or improvement while receiving Copaxone, Glatopa, or glatiramer acetate. IV. OTHER CRITERIA Members will not use Copaxone, Glatopa, or glatiramer acetate concomitantly with other disease modifyin DOSAGE & INDICATIONS For the treatment of relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. NOTE: Glatiramer has been designated an orphan drug by the FDA for this indication. Subcutaneous dosage (glatiramer acetate 20 mg/mL injection solution

Risk of immediate post-injection reactions (in general, symptoms appear several months following treatment initiation), including transient chest pain (seek prompt medical attention if prolonged or.. Copaxone(glatiramer acetate): Relapsing forms of multiple sclerosis (MS). Not to be administered as IV or IM. Discontinue treatment if severe adverse event occurs The FDA has approved an expanded indication for Copaxone (glatiramer acetate injection, from Teva) to include the treatment of patients who have experienced a first clinical episode and have.

Copaxone (Glatiramer Acetate): Uses, Dosage, Side Effects

WebMD provides common contraindications for Copaxone Subcutaneous. Find out what health conditions may be a health risk when taken with Copaxone Subcutaneou Copaxone is indicated for the treatment of relapsing forms of multiple sclerosis (MS) (see section 5.1 for important information on the population for which efficacy has been established). Copaxone is not indicated in primary or secondary progressive MS. 4.2 Posology and method of administratio Copaxone (glatiramer acetate) is a combination of four amino acids (proteins) used to treat multiple sclerosis (MS) and to prevent relapse of MS. Copaxone will not cure MS, but it can make relapses occur less often. What Are Side Effects of Copaxone? Common side effects of Copaxone include Find everything you need to know about Copaxone (Glatiramer (Injection)), including what it is used for, warnings, reviews, side effects, and interactions. Learn more about Copaxone (Glatiramer. Indications and use. Copaxone 20 mg/mL once-daily: Treatment of ambulatory patients with Relapsing Remitting Multiple Sclerosis (RRMS), including patients who have experienced a single demyelinating event and have lesions typical of multiple sclerosis on brain MRI: To decrease the frequency of clinical exacerbations.

Copaxone should only be administered subcutaneously. Copaxone should not be administered by intravenous or intramuscular routes. The treating physician should explain to the patient that a reaction associated with at least one of the following symptoms may occur within minutes of a Copaxone injection: vasodilatation (flushing), chest pain, dyspnoea, palpitations or tachycardia (see section 4.8) Does COPAXONE Interact with other Medications? Severe Interactions . These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in. Glatopa® is a therapeutically equivalent generic of Copaxone® that offers the same dosing flexibility in 3-times-a-week 40 mg/mL and once-daily 20 mg/mL. Please see Important Safety Information, Medication Guide, Instructions for Use, and full Prescribing Information on this website

  1. Dive Insight: Teva has been losing share in the U.S. multiple sclerosis market as competition stiffens and generics to Copaxone, such Momenta Pharmaceuticals and Novartis' Glatopa, gain approval. Generic versions of Copaxone 20 mg have been on the market for several years, but dosing patents helped to protect Teva's 40 mg version until Mylan launched its copy last fall
  2. I have a question for all the Copaxone users as I am about to become a big pain in the *** for both Teva pharmaceuticals and kaiser north.. Is anyone having issues getting their medical provider to approve the new Copaxone? Here in northern CA those of us in the Kaiser health system are being denied access be cause the new dosing hasn't proven to have any better efficacy I am not a medical.
  3. EP 335 covered copaxone, a drug which contains the active ingredient glatiramer acetate to alleviate symptoms of multiple sclerosis ©Pixel-Shot/ADOBE STOCK On 10 September, the EPO destroyed a patent licensed to Teva which covers copaxone, a drug to target the symptoms of certain indications of multiple sclerosis
  4. The paper's author concluded that, in spite of its age, Copaxone is still widely used as a first-line treatment option, in part due to its effectiveness, the extensive data available, its safety profile, convenient dosing regimen (when compared to similar drugs), and the lack of a necessary monitoring program
  5. ister your Copaxone dose at the same time every day
  6. Indications and dose. Multiple sclerosis [relapsing-remitting] (initiated under specialist supervision) By subcutaneous injection. For Adult. 20 mg once daily, alternatively 40 mg 3 times a week, doses to be separated by an interval of at least 48 hours. Glatiramer acetate 40 mg/mL (Copaxone.

Arzneimittel, Kosmetik- & Pflegeprodukte bequem und günstig online bestellen. Erleben Sie zuverlässige pharmazeutische Beratung COPAXONE 40 mg should be given on the same 3 days each week, if possible for example, Monday, Wednesday, and Friday. Give your COPAXONE injections at least 48 hours (2 days) apart. Each COPAXONE 40 mg prefilled syringe is for single use (1 time use) only. The COPAXONE 40 mg dose is packaged in boxes of 12 prefilled syringes with needles attached Copaxone 40 mg/mL should be given, if possible, at the same time and on the same three days each week (for example, Monday, Wednesday and Friday) at least 48 hours apart. Do not change the dose or dosing schedule or stop using Copaxone without talking to your doctor. How to use i The U.S. Food and Drug Administration (FDA) has approved the three-times-a-week COPAXONE® 40mg/mL, a new dose of COPAXONE® on Jan 28, 2014. This new formulation will allow for a less frequent dosing regimen administered by injection for patients with relapsing forms of multiple sclerosis (MS) From the information currently available, it is expected that Copaxone will continue to be available by prescription in both the 20mg once daily dose, and the 40mg dose taken three times a week. What about insurance coverage for the generic or for Copaxone - will I be forced to switch from my current medication

COPAXONE® Dosing & Injection Routin

INDICATIONS AND USAGE COPAXONE® Injection is indicated for reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis. CONTRAINDICATIONS COPAXONE® Injection is contraindicated in patients with known hypersensitivity to glatiramer acetate or mannitol Copaxone, Teva's best selling drug, is widely used for the treatment of relapsing forms of multiple sclerosis and contains the active pharmaceutical ingredient glatiramer acetate. The Commission has indications that Teva's campaign, primarily directed at healthcare institutions and professionals, may have targeted competing products to.

COPAXONE® (glatiramer acetate injection) for Relapsing M

The present FDA-approved dose of Copaxone is 20 mg given daily via subcutaneous injection. The new dosing under review is double the concentration (40 mg) and is given three days per week (also via subcutaneous injection) versus every day. If FDA approved, a less-frequent treatment option for Copaxone may become available

What happens if I miss a dose (Copaxone, Glatopa)? Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. What happens if I overdose (Copaxone, Glatopa)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 Important Safety Information. Contraindication: COPAXONE ® is contraindicated in patients with known hypersensitivity to glatiramer acetate or mannitol. Immediate Post-Injection Reaction: Approximately 16% of patients exposed to COPAXONE ® 20 mg per mL compared to 4% of those on placebo, and approximately 2% of patients exposed to COPAXONE ® 40 mg per mL compared to none on placebo. Indication. Glatopa ® (glatiramer acetate injection) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.. Important Safety Information. Do not take Glatopa ® if you are allergic to glatiramer acetate, mannitol, or any of the ingredients. Copaxone; Mayzent; Plegridy. For Aetna commercial plans, Plegridy (peginterferon beta-1a) brand is more costly to Aetna than other alternatives (least cost alternatives) for certain indications. There is a lack of reliable evidence that Plegridy is superior to the least cost alternatives for the medically necessary indications listed below The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action

COPAXONE Dosage & Rx Info Uses, Side Effect

Copaxone National Multiple Sclerosis Societ

  1. Copaxone (glatiramer acetate) is an immunomodulator used to reduce the frequency of relapses in patients with multiple sclerosis (MS).It is not an interferon, but may be grouped with interferon betas Avonex and Betaseron; together the three first-line treatments are sometimes known as the ABC drugs for MS.The exact mechanism of action of Copaxone in patients with MS is unknown
  2. I'm on dimethyl fumarate (Tecfidera), the beta-interferons (Avonex, Betaferon, Extavia, Plegridy, Rebif), teriflunomide (Aubagio), glatiramer acetate (Copaxone) and natalizumab (Tysabri) - when should I get the vaccine? Prof Schmierer: You can get the vaccine at any time if you are on one of these
  3. istration (FDA) approved the first generic GA, Glatopa™, as fully substitutable for all indications for which Copaxone 20mg is approved; Glatopa also represents the first FDA-approved AP-rated, substitutable generic for treating patients with MS. Glatiramer.
  4. Copaxone Pharmacologic class: Immunomodulator Therapeutic class: Multiple sclerosis agent Pregnancy risk category B Action Unknown. Thought to alter immune processes believed to be responsible for pathogenesis of multiple sclerosis. Availability Injection: 20 mg lyophilized glatiramer acetate and 40 mg mannitol in single-use 2-ml vial (1-ml.
  5. The active ingredient in COPAXONE® 40mg/mL is glatiramer acetate (GA), a synthetic mixture of polypep-tides. GA is also known as copolymer 1 or Cop. 1. COPAXONE® 40mg/mL is supplied as a single-dose prefilled syringe. Broadly, the treatment consists of the injection of 40mg of GA three times a week, abbreviate
  6. Indications All FDA-approved Indications. Off Label Uses 2. ACTIMMUNE Drugs ACTIMMUNE. Aubagio, Tecfidera, Tysabri or Copaxone is not covered. Required Medical Information Diagnosis of relapsing forms of multiple sclerosis (relapsing-remitting MS or progressive-relapsing MS, or secondary

Copaxone (glatiramer acetate) dose, indications, adverse

In In re Copaxone Consolidated Cases, the Federal Circuit affirmed the district court decision finding four patents directed to a specific dosing regimen for using COPAXONE® 40 mg/ml to treat patients with relapsing multiple sclerosis invalid as obvious.One thing that caught my attention was the use of originally confidential statements to FDA as evidence of the state of the art that. 1 INDICATIONS AND USAGE 2 DOSAGE AND ADMINISTRATION 2.1 Dosing Information 2.2 Switching Patients from Tetrabenazine (XENAZINE®) to AUSTEDO 2.3 Dosage Adjustment with Strong CYP2D6 Inhibitors 2.4 Dosage Adjustment in Poor CYP2D6 Metabolizers 2.5 Discontinuation and Interruption of Treatment 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATION Copaxone, Glatopa, and generic glatiramer are all available in the same dosage forms with the same dosing regimens; references reviewed and updated. 02.12.19 05.19 RT4: added coverage for CIS and SPMS per Copaxone's updated FDA labeling; references reviewed and updated. 08.02.19 2Q 2020 annual review: added requirements for documentation o Copaxone 20 mg daily was FDA approved in 1996, and was later approved for the 3-times-a-week 40 mg dose in 2014. 2 Glatopa, the first generic version of Copaxone, was approved as a 20 mg/mL one-time-daily dose MS therapy in 2015 Indications for Prior Authorization: Relapsing remitting multiple sclerosis (RRMS) Secondary progressive multiple sclerosis (SPMS) Avonex, Betaseron, Copaxone 40mg, Glatopa, Plegridy and Rebif are preferred disease modifying agents for the treatment of multiple sclerosis when all the criteria below are met

Copaxone, Glatopa (glatiramer) dosing, indications

Teva Pharmaceutical Industries Ltd. (NYSE: TEVA) announced today that the U.S. Food and Drug Administration (FDA) has approved the Company's supplemental new drug application (sNDA) for three-times-a-week COPAXONE ® 40mg/mL, a new dose of COPAXONE ®.This new formulation will allow for a less frequent dosing regimen administered subcutaneously for patients with relapsing forms of multiple. Patents protecting Copaxone against generic competition, however, including therapies for big-value indications like chronic pain, migraine, and asthma. Importantly, that innovation will.

Mylan has celebrated a reversal from the European Patent Office that has seen a key patent protecting Teva's higher-strength 40mg/ml thrice-weekly version of Copaxone deemed invalid and revoked across Europe. Meanwhile, Teva has commented on the possibility of an appeal Copaxone is used for the treatment of relapsing remitting type multiple sclerosis. Studies indicate that it reduces the frequency of attacks and the severity of disability and appears to be most effective for patient with minimal disability. FDA-approved Indications: treatment of relapsing forms of multiple sclerosi

Indications. Copaxone is approved to treat the following conditions in adults: clinically isolated syndrome (CIS) relapsing-remitting MS (RRMS) active secondary progressive MS (SPMS) Mechanism of. the preparation and injection of COPAXONE pre-filled syringes and pens. 3.4 Missed Dose If a dose is missed it should be taken as soon as possible. If, however, it is closer to the time of the next dose, skip the missed dose and resume at the usual dosing schedule. For COPAXONE 20 mg/mL, avoid giving 2 injections in the same 12-hour period Copaxone (glatiramer acetate) 20 mg/mL prefilled syringe 1 syringe per day Copaxone (glatiramer acetate) 40 mg/mL prefilled syringe 12 syringes per 28 days Align criteria with labeled indications. Update combination MS therapy exclusion criteria wording to align with criteria for other MS agents. Add references for non-label-based criteria. New Formulation of COPAXONE® Offers Patients and Their Physicians Ability to Dose Less Frequently JERUSALEM--(BUSINESS WIRE)--Jan. 28, 2014-- Teva Pharmaceutical Industries Ltd. (NYSE: TEVA).. When I was dx'ed last fall my neuro gave me info on 3 studies: Rebif New Formulation vs placebo; efficacy of combining Avonex and Copaxone; and a natural history study, as an adjunct to the Avonex/Copaxone study. I declined all of them as I live about 450 kms from the research facility and being in a study involves monthly follow ups

INDICATIONS AND USAGE AJOVY is a calcitonin gene-related peptide antagonist indicated for the preventive treatment of migraine in adults. (1) DOSAGE AND ADMINISTRATION • For subcutaneous use only. (2.1, 2.2) • Two subcutaneous dosing options of AJOVY are available to administer the recommended dosage: 225 mg monthly, o Infectious Disease > COVID-19 CDC Updates Contraindications to COVID-19 Vaccination — Casts wider net on allergic reactions to vaccine components. by Molly Walker, Associate Editor, MedPage. Adverse events reported with the Copaxone group were consistent with the known safety profile of the existing 20-mg formulation. Results from the study led the FDA to approve Copaxone 40 mg 3 times a week in the year following the study's publication. Conclusion: Copaxone 40 mg 3 times weekly is an effective and safe treatment for RRMS. 4 Copaxone is a disease modifying drug (DMD) for relapsing remitting MS.. You have fewer relapses than you might have had with no treatment and any relapses you do have should be less severe.. Copaxone is a moderately effective (category 1.1) DMD; in clinical trials people taking Copaxone had about 30% fewer relapses than people taking placebo. In clinical trials, MRI scans showed people taking.

6.2 Therapeutic indications Brabio® and Copaxone® are both licensed for the treatment of relapsing forms of MS.3-5,7 The Summary of Product Characteristics (SmPC) of both medicinal products contain a clear statement that they are not indicated in primary or secondary progressive MS.3-5,7 Recommendatio Copaxone (glatiramer acetate) is a prescription medicine for multiple sclerosis (MS), clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults. It is not known if Copaxone is safe and effective in children under 18 years of age. It is not known if Copaxone will harm your unborn baby if pregnant or if Copaxone passes into your breast milk Copaxone and Glatopa are indicated for the treatment of patients with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults

NDC 68546-317 Copaxone Glatiramer Acetate

Drug Name Dosing regimen Maximum Dose Glatiramer acetate (Copaxone) 20 mg SC QD or 40 mg SC TIW 20 mg/day or 40 mg TIW Glatiramer acetate (Glatopa) 20 mg SC QD 20 mg/day VI. Product Availability Drug Name Availability Glatiramer acetate (Copaxone) Single-dose, prefilled syringe: 20 mg/mL, 40 mg/m • If you miss a dose, take your COPAXONE ® as soon as you remember. If it's nearer to the time of your next scheduled dose, skip the missed dose and resume your usual dosing schedule. If you have any questions about missing a dose, contact Teva's Shared Solutions ® at 1-800-887-8100 or your healthcare provider for assistance

Dosing Information. There is only one standard recommended dose of Copaxone, regardless of your age or weight. As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so. (Click Copaxone Dosage for more information. Glatiramer Acetate Injection from Mylan is an FDA-approved therapeutic equivalent to Copaxone ® (glatiramer acetate injection), available in two doses. 20 mg/mL. for once-daily Injection. 40 mg/mL. 3-times-a-wee

Teva Has Got Potential - And The Complexity To Go With It

The indications below including FDA-approved indications and compendial uses are considered covered benefits provided that all the approval criteria are met and the member has no exclusions to the prescribed therapy. A. FDA-Approved Indications 1. Copaxone is indicated for the treatment of patients with relapsing forms of multiple sclerosis (MS) B. Other diagnoses/indications 1. Refer to ERX.PA.01 if diagnosis is NOT specifically listed under section III (Diagnoses/Indications for which coverage is NOT authorized) II. Continued Therapy A. Multiple Sclerosis (must meet all): 1. Currently receiving medication via a health plan affiliated with Envolve Pharmacy Solutions o Over seven years, COPAXONE and tolerability of three-times weekly dosing regimen of glatiramer acetate in relapsing-remitting multiple sclerosis patients: Up to 7-year results of the. Glatiramer acetate is a disease-modifying treatment (DMD) for relapsing remitting MS.Originally called copolymer 1, it has been marketed by the trade name of Copaxone and was approved for use in the US in 1996, Australia in 1999 and the UK in 2000.. It was discovered accidentally in 1968 by Israeli researchers who were trying to synthesize the myelin base protein so they could induce.

Contacts. Teva Pharmaceutical Industries Ltd. IR Contacts: United States Kevin C. Mannix, (215) 591-8912 Ran Meir, (215) 591-3033 Israel Tomer Amitai, 972 (3) 926-7656 or PR Contacts: Israel Iris. Why Defendants Prevailed: As early as 1996, when it approved the 20 mg daily dosage for Copaxone, the FDA suggested to Teva to explore less frequent dosing of GA. Moreover, various prior-art references disclosed that daily injections may be unnecessary and that a 40 mg dosage strength may present a similar side effect profile as the 20 mg. The National Multiple Sclerosis Society issued dosing recommendations for MS disease-modifying therapies (DMTs) for COVID-19 vaccinations 2.1 Dosing Information The recommended dose of REBIF is either 22 mcg or 44 mcg injected subcutaneously three times per week . REBIF should be administered, if possible, at the same time (preferably in the late afternoon or evening) on the same three days (e.g., Monday, Wednesday, and Friday) a FDA approves new dosing for Copaxone. The U.S. Food and Drug Administration has approved a new, less frequent dosing schedule for Copaxone (glatiramer acetate). The new schedule uses a higher dose (40 mg instead of the usual 20 mg), but injections are only three times per week (instead of daily)

Copaxone Dosage & Drug Information MIMS Thailan

HERTFORDSHIRE, England and PITTSBURGH, Aug. 25, 2015 /PRNewswire/ -- Mylan N.V. (Nasdaq: MYL) today announced that the U.S. Patent and Trademark Office (PTO) has instituted inter partes review (IPR) proceedings against two Copaxone® 40 mg/mL patents, U.S. Patent Nos. 8,232,250 and 8,399,413, owned by Yeda Research & Development Co., Ltd. and licensed to Teva Pharmaceuticals Industries Ltd Gilenya (fingolimod) is a prescription drug. It's used to treat relapsing forms of multiple sclerosis (MS) in adults and children ages 10 years and older. MS is an illness in which your immune. Copaxone moves toward Japanese regulatory approval by MSUK » Thu Nov 13, 2014 12:12 pm Teva Pharmaceutical Industries Ltd. multiple sclerosis treatment Copaxone is progressing toward regulatory approval in Japan Dosing . The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so

Copaxone gains expanded indication - MP

GLATIRAMER helps to decrease the number of multiple sclerosis relapses in people with relapsing-remitting forms of the disease. The medicine does not cure multiple sclerosis.Compare interferon betas Copaxone / Plegridy is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults (3, 5). Rebif is an interferon beta indicated for the treatment of patients with relapsing forms of multipl For more than 20 years, Copaxone (glatiramer acetate, Teva), a non-biological complex drug, has been a safe and effective treatment option for multiple sclerosis. In 2016, a follow-on glatiramer acetate product (FOGA, Synthon) was approved in the EU. Traditional bulk-based methods and high-resolutio Managing a chronic illness can be difficult enough without worrying how you're going to pay for your medications. Contact us for help.. Teva Pharmaceutical Industries (Teva), the maker of the multiple sclerosis drug Copaxone, allegedly boosted the drug's price tag from $17,000 to $73,000 per year—turning an already pricy medication into a completely inaccessible one for many

Dosing Considerations. Because natalizumab increases risk of progressive multifocal leukoencephalopathy (PML), it is recommended for patients who have had an inadequate response to, or are unable to tolerate, an alternate multiple sclerosis therapy A clinical advantage of 60 mg/day vs. 60 mg twice a day dosing has not been demonstrated; and the higher dose is less well tolerated. In 12-week studies, the reduction in mean pain scores, was significant by the end of week 1. A response to treatment, defined as a 30% reduction from baseline in 24-hour average pain severity on a 0 to 10 scale.

Contraindications for Copaxone Subcutaneou

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